In severe cases, the skin can become leathery

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In severe cases, the skin can become leathery and crackled. A steroid cream may hasten recovery. If the rash persists despite these measures, a visit to the dermatologist may be needed to find out what other substances may be causing a reaction. We carried out subanalyses on deaths from prevalent cancers (cancers detected at the first screening round) and deaths from incident cancers (cancers detected at screening rounds 2 to 5) plus cancers detected between screening rounds and cancers detected within one year of the last screen (interval cancers). We used Cox proportional hazards model to calculate hazard ratios with 95% confidence intervals. A P value of 0.05 was used as the cut off for statistical significance.

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